Chat with us, powered by LiveChat
The Best Pharmacy Software Since 1981

What Are the Most Common Frustrations of Independent Pharmacy Owners Today?

October 23, 2025
A frustrated pharmacist

Owning and operating an independent pharmacy is both rewarding and challenging. Independent pharmacy owners play a vital role in their communities, providing personalized care and trusted services that chain pharmacies often cannot match. But behind the counter, pharmacy owners are facing growing frustrations that threaten both profitability and sustainability.

The three most common challenges facing independent pharmacies today are PBM reimbursements and DIR fees, staffing shortages, and inventory management issues. Each of these issues impacts daily operations and long-term success. Fortunately, modern tools—such as a robust pharmacy software—are helping owners take back control.

Let’s explore these frustrations in more detail and show how the best pharmacy software, like Datascan, is helping independent pharmacy owners tackle them head-on.

1. PBM Reimbursements and DIR Fees

One of the greatest frustrations for independent pharmacy owners today, even despite more transparency, comes from Pharmacy Benefit Managers (PBMs). PBMs control reimbursements for prescription medications and impose Direct and Indirect Remuneration (DIR) fees—retroactive charges that can dramatically cut into profits.

DIR fees have been historically problematic because they can be unpredictable and collected months after the point of sale. This leaves pharmacy owners uncertain about their true margins, making it nearly impossible to forecast revenue accurately. According to many independent pharmacy owners, PBM reimbursements and DIR fees are the single largest financial burden they face today.  Fortunately, many plans now display a DIR fee at the time of adjudication, at least offering some level of transparency in their greedy practices.

How Datascan Helps Combat DIR Fees

Datascan understands the strain DIR fees place on independent pharmacies. The best pharmacy software includes robust reporting tools that allow pharmacy owners to track reimbursements more closely and identify trends. By gaining real-time visibility into claims, you can:

  • Monitor PBM reimbursements as they happen.
  • Catch discrepancies and underpayments quickly.
  • Understand performance metrics tied to DIR fee structures.

This level of transparency helps independent pharmacy owners make smarter business decisions and push back against the unpredictability of DIR fees.  Datascan also has a one-of-a-kind built-in “patient profit picture” within our pharmacy management software that helps pharmacy staff analyze patients as a whole, instead of just looking at a single prescription.  The patient profit picture breaks down patient margins over the last year, in 30, 60, 90, and 365-day increments, totals the number of prescriptions and margins, accounts for any OTC purchases, and even shows linked family members. While PBMs may challenge your ability to make a profit, the best pharmacy software, like Datascan, offers unique features to help combat their clawbacks.

2. Staffing Issues

Staffing has become another top frustration for independent community pharmacy owners. From pharmacists to pharmacy technicians, the entire industry is struggling with shortages and qualified people. The problem is twofold: fewer qualified candidates entering the workforce, and higher levels of burnout among existing staff.

For independent pharmacy owners, staffing challenges mean longer hours, increased stress, and sometimes reduced service to patients. Owners are often left asking: How can we accomplish more with fewer staff?  How can we alleviate employee stress and burnout?

Automation to Help Staff

This is where automation makes a huge difference. The best pharmacy software systems are designed to streamline daily operations, so your staff can focus on patient care instead of repetitive tasks. Key automation features include:

  • Automated refill management to reduce manual input.
  • Automated refill requests to doctors to ensure patients never go without medication.
  • Centralized workflow management to keep everyone on the same page.
  • Automated text messages and emails to keep you connected to your patients.

By maximizing system automation, pharmacies can reduce the administrative burden on staff, improve efficiency, and even reduce the need for additional hires. This not only helps combat staffing shortages but also prevents burnout among existing employees. You are already paying monthly for the pharmacy computer system, why not use the built-in tools to make it work for you, and in essence, pay you back!

3. Inventory Management

Inventory management is another top frustration for independent pharmacy owners. Stocking too much of one medication ties up cash flow, while running out of drugs risks patient satisfaction and compliance. The complexity of managing your inventory and finding the correct balance between stock and custom ordering makes it one of the most time-consuming and high-cost aspects of running a pharmacy.

How Datascan Simplifies Inventory with Perpetual Inventory Management

Datascan’s pharmacy software takes the guesswork out of inventory management. With a perpetual inventory system, pharmacy owners can track stock levels in real time, ensuring medications are always available when patients need them. The pharmacy management system provides:

  • Comprehensive Inventory Reporting: View usage trends and quickly identify slow-moving or excess stock.
  • EDI Integration with Wholesalers: Streamline ordering and receive data directly from your wholesalers
  • Inventory Forecasting: Predict future demand with precision, so you order the right medications at the right time.
  • Easy to set reorder points to help with automated ordering
  • Datarithm Integration: Leverage advanced inventory analytics to optimize stocking levels and maximize profitability.

By combining these features, independent pharmacy owners can reduce waste, improve cash flow, and provide better service to patients.

The Role of Pharmacy Software in Modern Independent Pharmacies

The frustrations facing independent pharmacy owners today—PBM reimbursements, DIR fees, staffing issues, and inventory management—are not going away anytime soon. However, choosing the best pharmacy software can help combat these challenges. 

With Datascan’s 5-star rated pharmacy software, independent pharmacy owners can:

  • Better analyze reimbursements.
  • Automate workflows to reduce staffing pressure.
  • Optimize inventory with perpetual management, forecasting, and advanced analytics.

These tools not only alleviate daily frustrations but also position pharmacies for long-term success.

Why Independent Pharmacies Choose Datascan’s software for pharmacies

Independent pharmacies thrive when they combine personalized care with efficient operations. That’s why so many choose Datascan as their pharmacy software partner. With over four decades of experience serving independent pharmacies, Datascan has built pharmacy management systems that aren’t just functional—they are tailored to the unique needs of community-based pharmacy owners.

Here’s why pharmacies trust Datascan:

  • Focused on Independent Pharmacies: Unlike large private equity-owned software providers, Datascan is built specifically for independent pharmacies and focuses on you.
  • Comprehensive Features: From DIR fee reporting to perpetual inventory, every tool is designed to tackle real-world challenges and help you accomplish more for less.
  • Ease of Use: Pharmacy staff of all skill levels can learn and navigate the pharmacy software quickly.
  • Proven Results: Pharmacies using Datascan report improved efficiency, reduced inventory costs, and better reimbursement insights.

Final Thoughts

Independent pharmacy owners face significant challenges today. PBM reimbursements and unpredictable DIR fees cut into profits, staffing shortages and difficulty hiring the right staff can strain operations, and inventory management can be overwhelming. But while these frustrations are common, they don’t have to hinder your success.

The right pharmacy software system can make all the difference. Datascan’s pharmacy management software helps independent pharmacy owners overcome these challenges with tools designed for real-world needs: reimbursement visibility, workflow and task automation, and perpetual inventory management.

By investing in the best pharmacy software like Datascan, independent pharmacy owners can shift their focus back to what matters most: delivering exceptional care to their patients and ensuring the long-term success of their business.

CEO of Datascan standing in the doorwayKevin Minassian is the President of Datascan Software. Under his leadership, the company rapidly expanded to provide pharmacy management software on a national level. Over the last 15+ years, he has ensured that Datascan has continuously evolved to offer innovative solutions for independent pharmacies while still offering world-class customer support. He is passionate about helping independent pharmacies to remain competitive, achieve success, and offer the very best service to their communities.